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9 There is a need for further longitudinal studies to confirm safety, which may slow adoption in broader patient populations

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These enzymes are important for the breakdown of sugar molecules into other types of molecules, the production of certain brain chemicals (for example, neurotransmitters), the production of several other essential molecules, and maintaining the body's ability to defend against free radicals

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Proteomic analysis of neuron progenitor cells from AD patients and isogenic controls Neuron progenitor cells were derived from human iPSCs (AD4 harbouring PSEN1-E9 mutation, isogenic control corrected for PSEN1-E9 mutation, and healthy control stem cell lines)