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elegans expressing mutants SOD1 A4V , SOD1 G37R , or SOD1 G93A (Oeda et al., 2001)

10.1073/pnas.86.2.471

October 3, 2025

M., Gerber, C

Recent data demonstrate that acute central administration of 5 g of the centrally selective TGR5 agonist, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-4-isoxazolecarboxamide, significantly reduces body weight gain in mice

Because DSIP is studied in the context of sleep architecture normalization, stress response modulation, and HPA axis regulation, it is a subject in experiments related to sleep-stress interactions and emotional well-beingwithout implying outcomes outside of a research setting.