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BPC-157 falls under the S0 Unapproved Substances category, a blanket ban covering any pharmacological substance not currently approved by any governmental regulatory health authority for human therapeutic use

In mouse models of cecal ligation and puncture (CLP)-induced sepsis, plasma-derived EVs affected RBC deformability, increasing RBC rigidity [387]

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activation of cytochrome c, inactivation of complex I of the electron transport chain and the apoptotic pathways