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Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic, debilitating disease characterised by a wide range of symptoms that severely impact all aspects of life

NAD+ is a critical coenzyme involved in cellular energy metabolism, widely studied for neuroprotective properties

The selection process involved an initial screening of titles and abstracts by two independent reviewers to identify studies that met our criteria

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However, stronger muscles support joints reducing injury risk and improving rehabilitation outcomes

[8] This is not a high-income issue either, Africa has seen the number of overweight children under 5 years old increase by 12% since 2000.[8] In Asia, almost half of children under 5 are overweight or living with obesity.[8] The health risks of obesity, as well as additional healthcare costs are significant