It establishes cellular antioxidant defense by transcriptionally activating antioxidant genes (e.g., SOD2, CAT, GCL) and reductive molecules (e.g., GSH, Trx), while downregulating pro-oxidant molecule synthesis, thereby directly scavenging or neutralizing excess ROS [134]
Patients with endometriosis have aneuploidy rates to their age-matched peers in the in vitro fertilization population
10.1016/j.cbpc.2014.04.005 30 HerreroA.ThompsonK
N.Guimares-PintoK.Amorim da CostaA
Previous research suggests that NAC may promote the nuclear translocation of Nrf2 [14] or activate NF-B signaling pathways [63], leading to increased expression of SOD and GSH-Px, thereby reducing excessive ROS that damage mitochondria in mouse oocytes
Suggestive evidence was observed between the level of retinol and NSCLC risk (IVW method: OR = 0.29