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While excessive levels of ROS can cause apoptosis in cancer cells, moderate ROS levels promote tumor development and progression (49)

Frohman LA, Kineman RD

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CD44v-dependent upregulation of xCT is involved in the acquisition of cisplatin-resistance in human lung cancer A549 cells

Via high-butyrate diet intervention and adoptive transfer experiments, it confirmed that a high-butyrate diet can induce the differentiation of follicular Tregs through HDAC inhibition, suppress the production of type II collagen (CII)-specific autoantibodies, and reduce joint swelling and bone erosion