Key findings included: Nearly 16% non-placebo-adjusted weight loss on 2.4 mg weekly berobenatide No weight-loss plateau observed through 32 weeks of extension treatment Successful transition from weekly induction to monthly maintenance dosing Favorable gastrointestinal tolerability despite rapid dose escalation These results provide proof-of-concept for monthly GLP-1 therapy while maintaining competitive efficacy
So lets break it down in therapist language: what it is, what the science actually supports, and why this is going to land in your treatment room more often next year
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10.1016/j.neuron.2008.01.003 Neuron Summary Keywords blood-brain barrier, amino acid transport, facilitative transport, active transport, cell polarity, luminal membrane, abluminal membrane, endothelial cells Citation Zaragoz R (2020) Transport of Amino Acids Across the Blood-Brain Barrier