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Doctors typically use B12 shots to treat vitamin B12 deficiency

This applies to all regions (US, UK, EU, Australia)

10.1093/ajcn/nqac106 292

Key target genes include those encoding components of the electron transport chain (ATP synthase subunits, cytochrome c), fatty acid oxidation enzymes (medium-chain acyl-CoA dehydrogenase, carnitine palmitoyltransferase 1), and transcription factors that amplify the metabolic signal (PGC-1 itself, NRF-1)

Boston, MA: Harvard Health Publishing (2013)

Results The study revealed that liposomal glutathione supplementation exhibited superior bioavailability compared to non-liposomal supplementation