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Studies by Pickart and colleagues have demonstrated that this silencing allows delivery of non-toxic copper into cells, distinguishing the complexed form from free copper ions that would readily catalyze oxidation

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Not surprisingly, ALA could alleviate all of these deleterious changes in aged kidneys [136,137,138]

Specifically, [Ca 2+ ] cyt rapidly increased to the peak value in leaf 6 at ~230 s upon treatment on leaf 1 with GSH rather than sorbitol (Fig