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Whilst minor trauma and stress are common triggers, vitamin B12 deficiency represents an important yet often overlooked cause of persistent oral ulceration

The Neuroscientist 28, 222237

Its not yet known whether GLP-1s can flip this switch, but there is a medical precedent for this, Schwartz says

Thus, in endothelial cells exposed to chronic hyperglycemia, sitagliptin treatment for 3 weeks decreased ROS production, 41 while in animal model, sitagliptin antitumoral effects were mediated via ROS inhibition

The gap between demonstrating a mechanism in cell culture and demonstrating meaningful health outcomes from an oral supplement is enormous