OxS is usually defined as Sa physiologically significant alteration in redox status resulting from an overproduction of reactive oxygen species (ROS) and/or a deficiency in antioxidant protective mechanisms [6]
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However, Dihexa may not be recommended for patients with certain medical conditions or those who are pregnant or breastfeeding
In dipeptidase deficiency, it remains to be established if there is a relationship between the biochemical defect and the clinical symptoms
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the contents of metabolites, such as PC, PS, and PE were significantly up-regulated, and the levels of up-regulated Autophagy - other, Necroptosis and ErbB signaling pathway, and down-regulated Sphingolipid metabolism, D-Amino acid metabolism metabolic pathway, to some extent The metabolic pathways of Sphingolipid metabolism and D-Amino acid metabolism were down-regulated to alleviate the disorders of glycerophospholipid and amino acid metabolism to a certain extent, thus alleviating the abnormalities of liver lipid metabolism
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