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Oral lipoic acid supplements are better absorbed on an empty stomach than with food: taking lipoic acid with food (versus without food) decreased peak plasma lipoic acid concentrations by about 30% and total plasma lipoic acid concentrations by about 20% (8)

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Citrate and oxide are harsher at higher doses

Efficacy: Literature shows that tacrolimus indeed promotes repigmentation of the vitiligo lesions, particularly effectively in sensitive areas where steroid use may not be indicated