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Emerging clinical trial methodologies, such as adaptive designs that allow protocol modification based on interim analyses and seamless phase II/III designs that integrate early data into confirmatory stages, may improve trial efficiency and accelerate translation into effective therapies 80 (Fig

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Oxidative and Nitrosative Stress in ADHD: Possible Causes and the Potential of Antioxidant-Targeted Therapies

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Am J Hum Genet 2017;101:630-7