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It establishes the future path for delivering other peptide drugs through transdermal patches as well

Further studies are needed to determine the level of any signal convergence downstream of PPG neurons, such as at the level of the arcuate nucleus, which is both accessible for systemically administered GLP1RAs and contains axon terminals from PPG neurons (Ast et al., 2020)

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In addition the market for weight loss drugs was considered too small to be commercially viable (Gilbert, Rosenthal, Jan 2024

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