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[1] [3] The relationship between GLP-1 medications and tiredness likely involves several factors

A literature review article published in 2023 summarized the results of three clinical trials (SUSTAIN, PIONEER and STEP) on the weight loss effect of semaglutide

They improve insulin sensitivity, which helps redirect nutrients away from fat storage

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7 , 21 Interestingly, another study reported that MALAT1 knockdown promotes ferroptosis in ectopic endometrial stromal cells in endometriosis, suggesting a potential connection between MALAT1 and ferroptosis regulation

So it's really interesting how this field is evolving because the omics, as you put it, whether it's proteomics, and now we're learning also about the epigenome and what brings us to the potential that this class of drugs would have an impact on health span in all people, not just those who are obese