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Preventing Over-treatment: While B12 is a water-soluble vitamin and is generally considered safe, injections are a medical procedure

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They should be used cautiously and ideally under medical guidance

The findings compiled in this table directly inform Section 9 (Discussion) in three key areas: regarding clinical significance, it supports the prioritization of stratified interventions based on nutrients with strong evidence (e.g., dietary fiber and EPA/DHA), particularly for inflammatory depression subtypes (65, 124)

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15 The plasma concentration of GSH is low because of its rapid turnover, and more than 80% of plasma GSH is removed by the kidney