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Researchers are expected to operate within their own institutional ethics, Control of Substances Hazardous to Health (COSHH), and biosafety frameworks

The phase 2 trial for type 2 diabetes used similar starting doses to the obesity trial, with gradual titration

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Subsequent physiology experiments and development of the first FDA-approved GLP-1/2 agonists contribute to this tales rising action. Nearly 40 years after GLP-1 and GIP were first cloned, our saga appears to be reaching its climax, as medications like Wegovy and Mounjaro are poised to become blockbuster treatments for obesity