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Given the emerging understanding of the gut-testicular axis and how gut-derived endotoxins may suppress testosterone (Tremellen, 2016), this property is potentially relevant to hormone health

Metformin, originally prescribed for diabetic individuals, has been recognized for its significant cardiovascular protective properties

Genetic polymorphisms in the human selenoprotein P gene determine the response of selenoprotein markers to selenium supplementation in a gender-specific manner (the SELGEN study)

Epub 2014 Sep 22

Impaired homocysteine metabolism-mediated moderate hyperhomocysteinemia (caused by folate deficiency, vitamin B 6 deficiency, or by methionine excess) might thus have primarily pro-oxidant effects resulting from an altered extra- and intracellular redox potential that can affect essential vascular functions

194,195 In addition, some studies suggest elevated homocysteine levels may be correlated with high androgen levels and fertility problems in women with PCOS