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A phase 2 trial of semaglutide 2.4 mg in 71 cirrhotic patients confirmed an acceptable safety profile without significant decompensation events, although the primary histological endpoint was not met, possibly due to the limited ability of antifibrotic remodeling to achieve biopsy-detectable fibrosis stage improvement in established cirrhosis over 48 weeks [46]

Lasschuijt MP, Mars M, de Graaf C, Smeets PAM

Diuretics and electrolytes Blood pressure medications like thiazide diuretics or loop diuretics actively deplete potassium, sodium, and magnesium

10.1055/A-2379-6849/ID/RDR-2024-06-3045-0040/BIB 6 AhmedF.ArshadM

A randomised controlled trial of exenatide once-weekly in alcohol use disorder showed mixed results overall, with possible effects in certain subgroups

These medications work by mimicking a natural hormone that regulates appetite and digestion