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Therapeutic advances of miRNAs: a preclinical and clinical update

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The glutamatergic hypothesis proposes that NMDAR hypofunction governs the damage of PV fast-spiking GABAergic interneurons and their synchronization activity [89], resulting in the diverse SZ symptoms

In the STEP 1 clinical trial, for example, the average weight loss over 68 weeks was almost 15%, but this wasnt achieved with weekly Wegovy injections alone

Yes, but interactions are possible, so medical guidance is necessary before combining therapies

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