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Animals were monitored for welfare daily, and euthanasia was by cardiac puncture after isoflurane anesthesia

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Dermatologic Common (1% to 10%): Hair loss, rash, urticaria Postmarketing reports : Alopecia, angioedema, rash, urticaria Hair loss was reported in up to 5.8% of treated patients vs 1% placebo, with higher incidence associated with greater weight loss (20% or more)

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