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In addition to weight management, the drug is also approved to treat obstructive sleep apnea in people with obesity

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198,199 GRP78 (HSP70) contributes to 5-FU resistance in colorectal and ovarian cancer cells by modulating the PI3K/AKT/mTOR and c-Src/LSF/TS signaling pathways

Current evidence shows mixed and inconsistent results, with most studies reporting minimal weight changes

Going from 2.4 mg semaglutide to 1.7 mg often resolves tolerability issues without restart

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