The methionine component is mildly acidic in solution, which compounds the irritation if it's deposited in a concentrated bolus rather than diffusing gradually through the fat layer
The authors describe the high clinical benefit rate in their cohort as a clarion call for rigorous, systematic investigation, but thus far there has been no large-scale or prospective, controlled investigation for MCAS
Many traditional capsules lose potency during digestion, reducing their effectiveness
You are allergic to other local anesthetics
The commentary accompanying the original paper highlighted these results as evidence that senescent cell elimination could produce systemic rejuvenation rather than isolated organ-specific improvements (Krimpenfort & Berns, 2017)
Recovery feels more complete, addressing multiple tissue types simultaneously