Advances in experimental medicine and biology , 264 , 7984
10.1016/j.fsi.2023.109146 133 ShinS
Molecular Mechanisms of Incretin Receptor Agonism in Fibrosis The anti-fibrotic actions of incretin receptor agonists are likely mediated through a combination of direct receptor-mediated signalling and indirect systemic effects
At the beginning of his recent Vanderbilt Discovery Lecture on glucagon-like peptide-1 (GLP-1) receptor agonists, Daniel Drucker, MD, joked that the title for his presentation could be What I still dont understand about how GLP-1 works. Drucker is a pioneering scientist whose research contributed to the development of the blockbuster GLP-1 medicines used to treat diabetes and obesity
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In order to demonstrate the broad potential of modifying neurexins as a strategy for sustained antidepressant effect, we examine the regulatory mechanisms of neurexins and their biological role in sustained antidepressant effect in this section