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The primary endpoint was the progression rate of EVs at 2 years of follow-up (NCT 03736265)

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Consistent with the neurological complications and intellectual disabilities is that individuals with DS have a higher susceptibility to early onset Alzheimer's disease (AD) 7,8

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Grx5 participates in the biogenesis of [4Fe4S] clusters by interacting with ISCA1 of the mitochondrial homolog of the ironsulfur cluster assembly and ISCA2 of the cytosolic iron cluster [161,162]

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