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Underlying health conditions such as cardiovascular disease, diabetes complications, depression, or other chronic illnesses continue to affect sexual function regardless of tirzepatide treatment

It is an investigational drug in active Phase 3 trials

However, when compared to endogenous GLP-1, exendin-4 has a C-terminal extended (CEX) amino acid sequence, along with substitution of the N-terminal alanine-2 residue with glycine, which makes the peptide resistant to degradation by DPP4, resulting in a significantly longer half-life than endogenous GLP-1 [62]

Rome, Food and Agriculture Organization of the United Nations (FAO Plant Production and Protection Paper 15 Sup.)

Plant sterols and their role in combined use with statins for lipid lowering

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