6, Issue 2, pp
Introduction Chronic kidney disease (CKD) is characterized by chronic structural damage and dysfunction of the kidneys caused by a variety of etiological factors, with a duration of more than 3 months ( Although the pathogenesis of CKD is complex and diverse and multiple pathological processes interact during disease progression, the prevailing view suggests that the accumulation of gut-derived uremic toxins (GUTs) in vivo may be a central factor in the occurrence and progression of CKD ( Given the impact of GUTs on CKD, in recent years, researchers have attempted to reduce the production of GUTs by killing GUT-producing bacteria, reducing substrate uptake, and inhibiting the function of related enzymes to slow the progression of CKD ( Astaxanthin (AST) is a small-molecule fat-soluble pigment belonging to the carotenoid family, which is widely found in shrimp, crabs, salmon, oysters, algae and fungi ( To address the unresolved mechanisms of AST in CKD, this study combined network pharmacology prediction with experimental validation
investigation, O.T., F.D., E.M
These cells work cooperatively to maintain BBB integrity and prevent infiltration of potentially harmful cells and solutes into the CNS
Dietary supplements should not be used as a substitute for a balanced diet
10.1016/j.pt.2005.01.003 Trends Parasitol
