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FIGURE 9 Discussion Glutathione peroxidase is a crucial antioxidant enzyme that participate in restraining the harmful accumulation of intracellular hydrogen peroxide and is more effective than catalase at eliminating intracellular peroxides under various physiological conditions ( In the present study, the role of GPX1 in SGNs treated with peroxynitrite was explored via using ebselen and GPX1 deficient mice

Prostaglandins are synthesized from arachidonic acid using cyclooxygenase (COX), and you can inhibit prostaglandin response via aspirin or NSAIDs (e.g., ibuprofen)