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These procedures can result in a loss of cells that secrete intrinsic factor a protein in the stomach needed to absorb B12

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Others find systemic injections (in the abdomen) to be just as effective and much simpler to administer

Levels below the borderline range (150-180 pg/mL) are considered early B12 deficiency, and when vitamin B12 drops below 100 pg/mL, it clearly indicates a deficiency

Folic acid is also ineffective in the treatment of aplastic and normocytic anemias