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This encompasses inflammatory disorders (including acute kidney injury, neuroinflammation, and atherosclerosis) (14, 15), cancers (such as laryngeal, hepatocellular, breast, pancreatic, lung, and brain malignancies) (16, 17), infectious diseases (like tuberculosis and pyemia) (18, 19), and neurodegenerative and systemic disorders (including Alzheimers disease and leukemia) (20, 21)

In terms of GI side effects, nausea is very common, but it can also cause constipation, diarrhea, vomiting, and dry mouth

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Dolotov OV, Karpenko EA, Inozemtseva LS, et al.: Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus

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(Reference DerSimonian and Kacker24) Furthermore, between-study heterogeneity was measured using the I 2 statistic and Cochranes Q test