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And those who had been taking the drugs also appeared to have a slightly higher risk of gestational diabetes, blood pressure disorders and even preterm birth

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In the SURMOUNT-5 trial, tirzepatide produced 47 percent greater weight loss than semaglutide in a head-to-head comparison

Managing side effects during titration Side effects are most common during the first few weeks and at each dose increase

Bickel, 15 October 2025, Scientific Reports

However, the medicines are widely used, and the agency also stated: It is not yet clear whether the reported cases are linked to the medicines themselves or to the patients underlying conditions or other factors. Will Ozempic become a mental health drug