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3a) Consistent with a deleterious role for free iron in ASCVD, ApoE-/- mice exposed to chronic iron overload displayed exacerbated atherosclerosis likely secondary to VEC damage or death, which was attenuated by dietary iron restriction or iron chelation 62,63

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Therefore, given the widespread use of incretin agonists for obesity treatment and weight loss, it is important to recognize their effects in the gastrointestinal tract, which could constitute significant benefits in weight loss and cardiometabolic benefits, but can be associated with adverse effects that constitute a potential barrier to their use, particularly at higher doses

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While Ozempic has been shown to be highly effective, the need for regular injections can be a downside for some people, depending on their preferences

Our program includes a combination of FDA-approved weight loss medications like Semaglutide (Ozempic) , Tirzepatide (Mounjaro) , and Zepbound