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AA, FS-G, and TZ performed experiments, analyzed data, and prepared figures

In summary, these disorders share fundamental microbial alterations: 1) Structural dysbiosis manifested through disrupted Bacteroidetes / Firmicutes ratios and reduced -diversity

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KEAP1-dependent NRF2 activators Electrophilic compounds The most known NRF2 activators are electrophiles electron-deficient species able to form covalent bonds with electron-rich nucleophiles through a variety of chemical pathways which can covalently bind and modify cysteine residues in KEAP1 [273, 274]

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Role of oligouridylation in normal metabolism and regulated degradation of mammalian histone mRNAs