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Astrocytes, in contrast, play a dual role: while their dysfunction can promote oxidative stress and calcium dysregulation, they also retain protective mechanisms such as the Nrf2-GPX4 antioxidant pathway, representing a potential therapeutic target

doi: 10.1039/an9952000817 79 CayirADonerayHKurtNOrbakZKayaATuranMIet al

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However, quantitation of the lengths of the different zones of the growth plates indicated that the proliferating zone of the growth plate was modestly increased while the prehypertrophic zone was decreased in CartIR / mice compared to controls (Figure 2e and 2f)

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