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Curr Opin Gastroen 34:7180
From a histological point of view, atypical tumor glands, constituted by neoplastic epithelial cells, occur in dense desmoplastic stroma, a proper physical barrier promoting tumor growth and progression and contributing to hamper anti-tumoral response and therapeutics delivery [11,12,13,14]
Liver cirrhosis, hepatic steatosis, liver fibrosis, precirrhotic conditions
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