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Semaglutide, tirzepatide, and retatrutide representing mono-agonist, dual-agonist, and triple-agonist approaches respectively have been studied extensively in clinical trials focused on metabolic function and body composition

Be careful with claims that use medical language while still labelling the product for research use

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However, certain clinical scenarios require careful consideration and may benefit from specialist input before initiating treatment

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Many people regain some or all of the lost weight once GLP-1s are stopped, especially if diet and activity have not changed