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IGF-1 Elevation Increased HGH stimulates the liver to produce IGF-1, the downstream mediator responsible for many of growth hormone's tissue-level effects

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Unfortunately, given the absence of fitting contextual references, we can only speculate about the reasons, such as methodological aspects particular to MRS (e.g., voxel size and coverage) or characteristics of the study population (here: healthy, middle-aged subjects with no hearing loss compared to studies in presbycusis 13,29 )

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