We do not yet know whether they directly affect tumor growth and development independent of weight loss benefits, or if and how they impact the metabolic activity of tumors or influence inflammation within the tumor microenvironment. Elizabeth McDonald, MD, PhD Current options for reducing breast cancer in those at However, while these options can substantially reduce breast cancer incidence in high-risk individuals, they can also result in adverse events
Effectiveness depends on factors including degree of weight regain, time since surgery, procedure type, and adherence to lifestyle modifications
Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) Earlier in 2025, a small study in JAMA Ophthalmology focused on eye complications experienced by nine people who took GLP-1 antidiabetic drugs, including semaglutide
A few have spoken publicly about taking the medications, such as Rebel Wilson, Kelly Clarkson and Amy Schumer, as well as older celebrities including Oprah Winfrey, Elon Musk, Stephen Fry, Whoopi Goldberg and Kathy Bates, who has been keen to point out that most of her weight loss was from diet and exercise
These findings also highlight the need for ongoing surveillance of dermatological adverse events in GLP-1 receptor agonist users, they wrote in their paper, published Wednesday in The BMJ
It seems to be the miracle weve all been waiting for easy weight loss without the need for diet or exercise