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These effects are often more noticeable when treatment starts or when the dose increases, and they may lessen over time

doi: 10.1530/JOE-13-0221 [DOI] [PubMed] [Google Scholar] 77

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Diabetologia 60(9):16201629 Uusitupa M, Peltonen M, Lindstrom J et al (2009) Ten-year mortality and cardiovascular morbidity in the finnish diabetes prevention studysecondary analysis of the randomized trial

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