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The most commonly injured ankle structures, consisting of the anterior talofibular ligament (ATFL), calcaneofibular ligament (CFL), and posterior talofibular ligament (PTFL)

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The active caspase-1 converts pro-IL-18 and pro-IL-1 into IL-18 and IL-1, which further induces an inflammatory response and triggers pyroptosis [74, 88]