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doi: 10.3389/fragi.2021.727380 120 ThomsonRLBrinkworthGDNoakesMCliftonPMNormanRJBuckleyJDet al

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Comp Biochem Physiol C Toxicol Pharm

In contrast to the lack of brain entry of dopamine in vivo [68], our results with the targeted dopamine-nanoformulation using the BBB model combined with midbrain organoids indicate that the nanoformulation may help dopamine to reach the brain tissue after BBB penetration

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