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APR-246, also known as PRIMA-1MET, is a promising new therapeutic agent that targets TP53 mutated cancers

SGLT-2 Inhibitors The BMJ/MAGIC Group strongly recommends that SGLT-2 inhibitors be added to existing treatment for all patients with type 2 diabetes, cardiovascular disease, and chronic kidney disease

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The authors thank Scot Roberts and Bertrand Georges of Altimmune Inc

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