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However, while very beneficial in this realm, the consequences of these medications with regard to general anesthesia were not well understood prior to their Food and Drug Administration (FDA) approval
As illustrated in Figures 2, 3, decreased free carnitine was noted in a subset of CAMP autistic participants
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A recent report documented accumulation of the ceramide precursor sphingosine and C20:0, C22:0, C22:1, C24:0 and C24:1 ceramide species in mitochondria isolated from both 5xFAD mice and AD patient brains (Crivelli et al., 2024)
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