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Amiodarone and valproic acid Amiodarone is a drug used to treat arrhythmia, while valproic acid is an anticonvulsant

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Inspection of the BMI % phenotype revealed a heavy tailed distribution, so we further quality controlled the BMI % phenotype to remove outlier participants with BMI changes above 20% or below 45% (Extended Data Fig

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18,19,20 It may therefore act as a potent inhibitor of T cell activation and in turn affect in the ACPA production