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The proportion of TPA-stimulated ROS-forming PMN ( Figure 5F ) fluctuated nonspecifically over time until 9 h pi and dropped rapidly to a nadir at 12 h pi , when only 88% of PMN could be stimulated, before maintaining the baseline level until the end of the trial

In the skin, ROS are generated continuously, however, they can be eliminated by a variety of antioxidant substrates (Richelle et al., 2006)

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