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Why Tackling Weight Matters Excess weight poses significant health risks, including type 2 diabetes, heart disease, high blood pressure, sleep apnea, joint pain, and an increased likelihood of certain cancers

doi:10.1016/S2213-8587(22)00163-2 2

FDA-approved brand-name GLP-1 medications - Wegovy, Ozempic, Zepbound, Mounjaro - are products the FDA has reviewed as finished products for safety, efficacy, and manufacturing quality

The association of three-month percentage weight loss with gender and baseline BMI was assessed with the Mann-Whitney U test and the Pearson correlation coefficient, respectively

Obesity contributes to this issue, as it is linked with chronic, low-grade inflammation, which correlates with conditions such as insulin resistance, type 2 diabetes mellitus (T2DM), nonalcoholic fatty liver disease, and atherosclerosis [10]

Both oral and injectable GLP-1 medications can cause digestive side effects