Diabetes 54 , 10561063 (2005)
To achieve the best results and minimize the risk of side effects, patients should adhere to the prescribed dosing schedule and attend all follow-up appointments
A Strength of recommendation (SOR) A Good-quality patient-oriented evidence B Inconsistent or limited-quality patient-oriented evidence C Consensus, usual practice, opinion, disease-oriented evidence, case series The "Standards of Medical Care in Diabetes" guidelines published in 2015 by the American Diabetes Association (ADA) state that metformin is the preferred initial pharmacotherapy for managing type 2 diabetes
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Increase to 5 mg: After 4 weeks, increase the dose to 5 mg once weekly
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