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However, the therapeutic efficacy of natalizumab is associated with adverse effects, the article said

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Moreover, in patients with obesity and prediabetes or those with T2DM, a decrease in visceral fat was observed using GLP-1 RAs [43, 44]

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After being annotated by the Human Metabolome Database (HMDB) and statistical analysis by chemical classification, totally 29 metabolites that were significantly different between the two groups were identified and screened out (Fig

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