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In addition, when PKA and AMPK are inhibited in a dose-dependent manner, the cytotoxicity of glutamic acid is aggravated ( + /K + ATPase activity, and modulated the GLP-1 receptor in the rat choroid plexus in vitro ( Recent findings also suggest that GLP-1 modulates the SIRT1 pathway, which plays a crucial role in regulating inflammation and autophagy