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These lesions are associated with inflammation, demyelination, glial activation, and neuroaxonal degeneration, leading to compromised neuronal signaling [106]

Recent post hoc analysis from the ZETA trial also demonstrated that vandetanib treatment had significant prolonged median PFS (hazard ratio [HR], 0.43

& Yamagishi, S

Dietary patterns which focus on vegetables, fruits, legumes, nuts, whole grains, and fish have been shown to decrease ASCVD risk factors, with the strongest evidence for Mediterranean and plant-based diets [19, 20]

SURPASS J-combo study comparing people with T2DM in a Japanese population with a high HbA1c on oral antihyperglycemic monotherapy on 5, 10, or 15 mg of once weekly tirzepatide for 52 weeks showed an improvement of glycemic and lipid control, weight loss and reduction in blood pressure [57]

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